SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

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Summary: Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an...

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Bibliographic Details
Main Authors: Matteo D’Antonio, Jennifer P. Nguyen, Timothy D. Arthur, Hiroko Matsui, Agnieszka D’Antonio-Chronowska, Kelly A. Frazer
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Cell Reports
Subjects:
COVID-19
SARS-CoV-2
GWAS
eQTL
colocalization
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721015023

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http://www.sciencedirect.com/science/article/pii/S2211124721015023

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