The Reducing Effects of Pyrogallol-Phloroglucinol-6,6-Bieckol on High-Fat Diet-Induced Pyroptosis in Endothelial and Vascular Smooth Muscle Cells of Mice Aortas

The Reducing Effects of Pyrogallol-Phloroglucinol-6,6-Bieckol on High-Fat Diet-Induced Pyroptosis in Endothelial and Vascular Smooth Muscle Cells of Mice Aortas

In hyperlipidemia, pyroptosis in endothelial cells (ECs) induces atherosclerosis via the toll-like receptor 4 (TLR4) pathway. We evaluated the effects of Ecklonia cava extract (ECE) and pyrogallol-phloroglucinol-6,6-bieckol (PPB) on pyroptosis of ECs and vascular smooth muscle cells (VSMCs), which l...

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Bibliographic Details
Main Authors: Seyeon Oh, Myeongjoo Son, Chul-Hyun Park, Ji Tae Jang, Kuk Hui Son, Kyunghee Byun
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Marine Drugs
Subjects:
<i>ecklonia cava</i>
endothelial cells or vascular smooth muscle cells dysfunction
inflammasome
pyrogallol-phloroglucinol-6,6-bieckol
pyroptosis
Online Access:https://www.mdpi.com/1660-3397/18/12/648

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https://www.mdpi.com/1660-3397/18/12/648

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