Clinical development of metabolic inhibitors for oncology
Metabolic inhibitors have been used in oncology for decades, dating back to antimetabolites developed in the 1940s. In the past 25 years, there has been increased recognition of metabolic derangements in tumor cells leading to a resurgence of interest in targeting metabolism. More recently there has...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-01-01
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Series: | The Journal of Clinical Investigation |
Online Access: | https://doi.org/10.1172/JCI148550 |