High-capacity sample multiplexing for single cell chromatin accessibility profiling

High-capacity sample multiplexing for single cell chromatin accessibility profiling

Abstract Single-cell chromatin accessibility has emerged as a powerful means of understanding the epigenetic landscape of diverse tissues and cell types, but profiling cells from many independent specimens is challenging and costly. Here we describe a novel approach, sciPlex-ATAC-seq, which uses unm...

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Bibliographic Details
Main Authors: Gregory T. Booth, Riza M. Daza, Sanjay R. Srivatsan, José L. McFaline-Figueroa, Rula Green Gladden, Andrew C. Mullen, Scott N. Furlan, Jay Shendure, Cole Trapnell
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Genomics
Subjects:
Single-cell
Sequencing
Genomics
Chromatin
Perturbation
Screening
Online Access:https://doi.org/10.1186/s12864-023-09832-1

Internet

https://doi.org/10.1186/s12864-023-09832-1

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