Pan-Genome-Wide Association Study of Serotype 19A Pneumococci Identifies Disease-Associated Genes

Pan-Genome-Wide Association Study of Serotype 19A Pneumococci Identifies Disease-Associated Genes

ABSTRACT Despite the widespread implementation of pneumococcal vaccines, hypervirulent Streptococcus pneumoniae serotype 19A is endemic worldwide. It is still unclear whether specific genetic elements contribute to complex pathogenicity of serotype 19A isolates. We performed a large-scale pan-genome...

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Bibliographic Details
Main Authors: Ting Li, Jiayin Huang, Shimin Yang, Jianyu Chen, Zhenjiang Yao, Minghao Zhong, Xinguang Zhong, Xiaohua Ye
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Streptococcus pneumoniae
pneumococcus
bacterial genomics
genome-wide association study
pathogenicity
invasive pneumococcal disease
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04073-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04073-22

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