Computational pathology-based weakly supervised prediction model for MGMT promoter methylation status in glioblastoma

IntroductionThe methylation status of oxygen 6-methylguanine-DNA methyltransferase (MGMT) is closely related to the treatment and prognosis of glioblastoma. However, there are currently some challenges in detecting the methylation status of MGMT promoters. The hematoxylin and eosin (H&E)-sta...

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Bibliographic Details
Main Authors: Yongqi He, Ling Duan, Gehong Dong, Feng Chen, Wenbin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1345687/full