Internal Introns Promote Backsplicing to Generate Circular RNAs from Spinal Muscular Atrophy Gene
Human <i>survival motor neuron 1</i> (<i>SMN1</i>) codes for SMN, an essential housekeeping protein involved in most aspects of RNA metabolism. Deletions or mutations of <i>SMN1</i> lead to spinal muscular atrophy (SMA), a devastating neurodegenerative disease lin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-06-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/13/7/1145 |