Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines

Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines

ABSTRACT The PML (promyelocytic leukemia) protein is a member of the TRIM family, a large group of proteins that show high diversity in functions but possess a common tripartite motif giving the family its name. We and others recently reported that both murine PML (mPML) and human PML (hPML) strongl...

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Bibliographic Details
Main Authors: Nasser Masroori, Pearl Cherry, Natacha Merindol, Jia-xin Li, Caroline Dufour, Lina Poulain, Mélodie B. Plourde, Lionel Berthoux
Format: Article
Language:English
Published: American Society for Microbiology 2017-06-01
Series:mSphere
Subjects:
HIV-1
PML
TRIM19
TRIM5α
innate immunity
interferon
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00233-17

Internet

https://journals.asm.org/doi/10.1128/mSphereDirect.00233-17

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