Modulating the Blood–Brain Barrier: A Comprehensive Review

Modulating the Blood–Brain Barrier: A Comprehensive Review

The highly secure blood–brain barrier (BBB) restricts drug access to the brain, limiting the molecular toolkit for treating central nervous system (CNS) diseases to small, lipophilic drugs. Development of a safe and effective BBB modulator would revolutionise the treatment of CNS diseases and future...

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Bibliographic Details
Main Authors: Rory Whelan, Grainne C. Hargaden, Andrew J. S. Knox
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
blood-brain barrier (BBB)
CNS drug delivery
tight junction (TJ)
BBB permeability
BBB modulation
focused ultrasound
Online Access:https://www.mdpi.com/1999-4923/13/11/1980

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https://www.mdpi.com/1999-4923/13/11/1980

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