Intradiscal treatment of the cartilage endplate for improving solute transport and disc nutrition

Intradiscal treatment of the cartilage endplate for improving solute transport and disc nutrition

Poor nutrient transport through the cartilage endplate (CEP) is a key factor in the etiology of intervertebral disc degeneration and may hinder the efficacy of biologic strategies for disc regeneration. Yet, there are currently no treatments for improving nutrient transport through the CEP. In this...

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Bibliographic Details
Main Authors: Mohamed Habib, Shayan Hussien, Oju Jeon, Jeffrey C. Lotz, Peter I-Kung Wu, Eben Alsberg, Aaron J. Fields
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cartilage endplate
intervertebral disc degeneration
biotransport
spine biomechanics
low back pain
tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1111356/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2023.1111356/full

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