Therapeutic efficacy of a K5-specific phage and depolymerase against Klebsiella pneumoniae in a mouse model of infection

Abstract Klebsiella pneumoniae has become one of the most intractable gram-negative pathogens infecting humans and animals due to its severe antibiotic resistance. Bacteriophages and protein products derived from them are receiving increasing amounts of attention as potential alternatives to antibio...

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Bibliographic Details
Main Authors: Pei Li, Genglin Guo, Xiangkuan Zheng, Sixiang Xu, Yu Zhou, Xiayan Qin, Zimeng Hu, Yanfei Yu, Zhongming Tan, Jiale Ma, Long Chen, Wei Zhang
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Veterinary Research
Subjects:
Online Access:https://doi.org/10.1186/s13567-024-01311-z