Neurodegeneration in Multiple Sclerosis: The Role of Nrf2-Dependent Pathways

Neurodegeneration in Multiple Sclerosis: The Role of Nrf2-Dependent Pathways

Multiple sclerosis (MS) encompasses a chronic, irreversible, and predominantly immune-mediated disease of the central nervous system that leads to axonal degeneration, neuronal death, and several neurological symptoms. Although various immune therapies have reduced relapse rates and the severity of...

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Bibliographic Details
Main Authors: Paloma P. Maldonado, Coram Guevara, Margrethe A. Olesen, Juan Andres Orellana, Rodrigo A. Quintanilla, Fernando C. Ortiz
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
multiple sclerosis
Nrf2-dependent pathways
neuroinflammation
pannexin-1
glial cells
reactive oxygen species
Online Access:https://www.mdpi.com/2076-3921/11/6/1146

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https://www.mdpi.com/2076-3921/11/6/1146

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