SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice

SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice

Since SARM1 mutations have been identified in human neurological disease, SARM1 inhibition has become an attractive therapeutic strategy to preserve axons in a variety of disorders of the peripheral (PNS) and central nervous system (CNS). While SARM1 has been extensively studied in neurons, it remai...

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Bibliographic Details
Main Authors: Shaline V. Fazal, Clara Mutschler, Civia Z. Chen, Mark Turmaine, Chiung-Ya Chen, Yi-Ping Hsueh, Andrea Ibañez-Grau, Andrea Loreto, Angeles Casillas-Bajo, Hugo Cabedo, Robin J. M. Franklin, Roger A. Barker, Kelly R. Monk, Benjamin J. Steventon, Michael P. Coleman, Jose A. Gomez-Sanchez, Peter Arthur-Farraj
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Schwann cell
oligodendrocyte
myelination
SARM1
zebrafish
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1158388/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1158388/full

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