Cepharanthine Prevents Estrogen Deficiency-Induced Bone Loss by Inhibiting Bone Resorption

Cepharanthine Prevents Estrogen Deficiency-Induced Bone Loss by Inhibiting Bone Resorption

Osteoporosis is a common health problem worldwide caused by an imbalance of bone formation vs. bone resorption. However, current therapeutic approaches aimed at enhancing bone formation or suppressing bone resorption still have some limitations. In this study, we demonstrated for the first time that...

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Bibliographic Details
Main Authors: Chen-he Zhou, Jia-hong Meng, Yu-te Yang, Bin Hu, Jian-qiao Hong, Zheng-tao Lv, Kun Chen, Boon Chin Heng, Guang-yao Jiang, Jian Zhu, Zhao-hui Cheng, Wei Zhang, Le Cao, Wei Wang, Wei-liang Shen, Shi-gui Yan, Hao-bo Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
cepharanthine
osteoclasts
osteoporosis
Akt
JNK
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00210/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00210/full

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