Identification of a Novel Immune Landscape Signature for Predicting Prognosis and Response of Colon Cancer to Immunotherapy

Identification of a Novel Immune Landscape Signature for Predicting Prognosis and Response of Colon Cancer to Immunotherapy

PurposeTo construct an immune-related gene prognostic index (IRGPI) for colon cancer and elucidate the molecular and immune characteristics as well as the benefit of immune checkpoint inhibitor (ICI) therapy in IRGPI-defined groups of colon cancer.Experimental DesignTranscriptional and clinical data...

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Bibliographic Details
Main Authors: Zheng Wang, Jingru Song, Nisma Lena Bahaji Azami, Mingyu Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
colon cancer
immune-related gene prognostic index
weighted gene co-expression network analysis (WGCNA)
prognosis
signature
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.802665/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.802665/full

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