Transformation to small cell lung cancer after first-line afatinib treatment

Transformation to small cell lung cancer after first-line afatinib treatment

Acquiring resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is inevitable. Transformation to small cell lung cancer (SCLC) is reported as a possible mechanism of this acquired resistance. We describe the case of a 35-year-old man with lung adenocarcinoma harbori...

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Bibliographic Details
Main Authors: Takayuki Shiroyama, Shingo Nasu, Ayako Tanaka, So Takata, Kentaro Masuhiro, Hiromune Takada, Satomu Morita, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kunimitsu Kawahara, Tomonori Hirashima
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Respiratory Medicine Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221300711830039X

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http://www.sciencedirect.com/science/article/pii/S221300711830039X

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