Endurance exercise remodels skeletal muscle by suppressing Ythdf1-mediated myostatin expression

Abstract Exercise can improve health via skeletal muscle remodeling. Elucidating the underlying mechanism may lead to new therapeutics for aging-related loss of skeletal muscle mass. Here, we show that endurance exercise suppresses expression of YT521-B homology domain family (Ythdf1) in skeletal mu...

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Bibliographic Details
Main Authors: Xin Huang, Chenzhong Xu, Jie Zhang, Weiwei Wu, Zimei Wang, Qiuxiang Pang, Zuojun Liu, Baohua Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07379-5