Oncostatin-M Differentially Regulates Mesenchymal and Proneural Signature Genes in Gliomas via STAT3 Signaling

Oncostatin-M Differentially Regulates Mesenchymal and Proneural Signature Genes in Gliomas via STAT3 Signaling

Glioblastoma (GBM), the most malignant of the brain tumors is classified on the basis of molecular signature genes using TCGA data into four subtypes- classical, mesenchymal, proneural and neural. The mesenchymal phenotype is associated with greater aggressiveness and low survival in contrast to GBM...

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Bibliographic Details
Main Authors: Kumar Natesh, Dipali Bhosale, Aarti Desai, Goparaju Chandrika, Radha Pujari, Jayashree Jagtap, Ashish Chugh, Deepak Ranade, Padma Shastry
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615000020

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http://www.sciencedirect.com/science/article/pii/S1476558615000020

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