Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiovascular Remodelling in a Mouse Model of Advanced Atherosclerosis

Acetylsalicylic Acid Reduces Passive Aortic Wall Stiffness and Cardiovascular Remodelling in a Mouse Model of Advanced Atherosclerosis

Acetylsalicylic acid (ASA) is widely used in secondary prevention of cardiovascular (CV) disease, mainly because of its antithrombotic effects. Here, we investigated whether ASA can prevent the progression of vessel wall remodelling, atherosclerosis, and CV complications in apolipoprotein E deficien...

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Bibliographic Details
Main Authors: Lynn Roth, Miche Rombouts, Dorien M. Schrijvers, Besa Emini Veseli, Wim Martinet, Guido R. Y. De Meyer
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
arterial stiffness
neutrophil–lymphocyte ratio
collagen
SMAD
elastin
aspirin
Online Access:https://www.mdpi.com/1422-0067/23/1/404

Internet

https://www.mdpi.com/1422-0067/23/1/404

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