The systemic and hepatic alternative renin–angiotensin system is activated in liver cirrhosis, linked to endothelial dysfunction and inflammation

Abstract We aimed to assess the systemic and hepatic renin-angiotensin-system (RAS) fingerprint in advanced chronic liver disease (ACLD). This prospective study included 13 compensated (cACLD) and 12 decompensated ACLD (dACLD) patients undergoing hepatic venous pressure gradient (HVPG) measurement....

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Bibliographic Details
Main Authors: Lukas Hartl, Benedikt Rumpf, Oliver Domenig, Benedikt Simbrunner, Rafael Paternostro, Mathias Jachs, Marko Poglitsch, Rodrig Marculescu, Michael Trauner, Roman Reindl-Schwaighofer, Manfred Hecking, Mattias Mandorfer, Thomas Reiberger
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28239-2