Effect of Skin Ion Channel TRPM8 Activation by Cold and Menthol on Thermoregulation and the Expression of Genes of Thermosensitive TRP Ion Channels in the Hypothalamus of Hypertensive Rats

Effect of Skin Ion Channel TRPM8 Activation by Cold and Menthol on Thermoregulation and the Expression of Genes of Thermosensitive TRP Ion Channels in the Hypothalamus of Hypertensive Rats

ISIAH (inherited stress-induced arterial hypertension) rats are characterized by high blood pressure and decreased <i>Trpm8</i> gene expression in the anterior hypothalamus. Thermosensitive ion channel TRPM8 plays a critical role in the transduction of moderately cold stimuli that give r...

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Bibliographic Details
Main Authors: Irina P. Voronova, Galina M. Khramova, Anna A. Evtushenko, Tamara V. Kozyreva
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
cold/menthol activation of TRPM8
gene expression
thermoregulation
hypertension
Online Access:https://www.mdpi.com/1422-0067/23/11/6088

Internet

https://www.mdpi.com/1422-0067/23/11/6088

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