Multidrug Intrinsic Resistance Factors in <named-content content-type="genus-species">Staphylococcus aureus</named-content> Identified by Profiling Fitness within High-Diversity Transposon Libraries
ABSTRACT Staphylococcus aureus is a leading cause of life-threatening infections worldwide. The MIC of an antibiotic against S. aureus, as well as other microbes, is determined by the affinity of the antibiotic for its target in addition to a complex interplay of many other cellular factors. Identif...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-09-01
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Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.00950-16 |