Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

Abstract Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-m...

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Main Authors: Jamie L. Felton, Maria J. Redondo, Richard A. Oram, Cate Speake, S. Alice Long, Suna Onengut-Gumuscu, Stephen S. Rich, Gabriela S. F. Monaco, Arianna Harris-Kawano, Dianna Perez, Zeb Saeed, Benjamin Hoag, Rashmi Jain, Carmella Evans-Molina, Linda A. DiMeglio, Heba M. Ismail, Dana Dabelea, Randi K. Johnson, Marzhan Urazbayeva, John M. Wentworth, Kurt J. Griffin, Emily K. Sims, On behalf of the ADA/EASD PMDI
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00478-y