Use of labelled cisplatin obtained by direct irradiation in a preliminary biodistribution study

Use of labelled cisplatin obtained by direct irradiation in a preliminary biodistribution study

This work presents the preparation of radiolabelled cis-dichlorodiammineplatinum (II), CDDP*, from its direct irradiation into a cadmium capsule, using the TRIGA MARK I IPR R-1 research reactor of the CDTN. The ability to detect CDDP* in Ehrlich tumour-bearing mice after administration via an intrav...

Full description

Bibliographic Details
Main Authors: Álvaro Dutra de Carvalho Júnior, Fabiana Moreira Abrantes, Maria Ângela Menezes, Alexandre Soares Leal, Valbert Nascimento Cardoso, Mônica Cristina de Oliveira
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2005-10-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Radiolabelled cisplatin
biodistribution
TRIGA research reactor
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700013

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700013

Similar Items