Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing

<p>Abstract</p> <p>Background</p> <p>Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorithms, each justified by theory, simulation, or ad hoc validation an...

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Bibliographic Details
Main Authors: Bickel David R, Yanofsky Corey M
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/63