Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes
Abstract There are many short-read variant-calling tools, with different strengths and weaknesses. We present a tool, Minos, which combines outputs from arbitrary variant callers, increasing recall without loss of precision. We benchmark on 62 samples from three bacterial species and an outbreak of...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-07-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-022-02714-x |