The DNA damage and regulatory strategy in hematopoietic stem cells after irradiation exposure: Progress and challenges

The hematopoietic system is susceptible to ionizing radiation (IR), which can cause acute hematopoietic failure or long-term myelosuppression. As the most primitive cells of the hematopoietic hierarchy, hematopoietic stem cells (HSCs) maintain lifelong hematopoietic homeostasis and promote hematopoi...

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Bibliographic Details
Main Authors: Yanying Liu, Naicheng Chen, Fang Chen, Hao Zeng, Lijing Yang, Junping Wang, Mengjia Hu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Radiation Medicine and Protection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666555723000746