Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface

Infections at the maternal-fetal interface can directly harm the fetus and induce complications that adversely impact pregnancy outcomes. Innate immune signaling by both fetal-derived placental trophoblasts and the maternal decidua must provide antimicrobial defenses at this critical interface witho...

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Bibliographic Details
Main Authors: Liheng Yang, Eleanor C Semmes, Cristian Ovies, Christina Megli, Sallie Permar, Jennifer B Gilner, Carolyn B Coyne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/79794