An ocular Th1 immune response promotes corneal nerve damage independently of the development of corneal epitheliopathy

An ocular Th1 immune response promotes corneal nerve damage independently of the development of corneal epitheliopathy

Abstract Proper sight is not possible without a smooth, transparent cornea, which is highly exposed to environmental threats. The abundant corneal nerves are interspersed with epithelial cells in the anterior corneal surface and are instrumental to corneal integrity and immunoregulation. Conversely,...

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Bibliographic Details
Main Authors: Alexia Vereertbrugghen, Manuela Pizzano, Florencia Sabbione, Irene Angelica Keitelman, Carolina Maiumi Shiromizu, Douglas Vera Aguilar, Federico Fuentes, Cintia S. de Paiva, Mirta Giordano, Analía Trevani, Jeremías G. Galletti
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Neuroinflammation
Subjects:
Corneal nerves
Neuropathy
CD4 T cells
Th1 response
Immunopathology
Online Access:https://doi.org/10.1186/s12974-023-02800-2

Internet

https://doi.org/10.1186/s12974-023-02800-2

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