Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain

Side chain oxidizedoxysterols have a unique ability to traverse lipophilic membranes. We tested thehypothesis that there is a net flux of 27-hydroxycholesterol from the circulationinto the brain using plasma samples collected from the internal jugular vein andan artery of healthy male volunteers. Tw...

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Bibliographic Details
Main Authors: Maura Heverin, Steve Meaney, Dieter Lütjohann, Ulf Diczfalusy, John Wahren, Ingemar Björkhem
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339882