Polyamine sharing between tubulin dimers favours microtubule nucleation and elongation via facilitated diffusion.

Polyamine sharing between tubulin dimers favours microtubule nucleation and elongation via facilitated diffusion.

We suggest for the first time that the action of multivalent cations on microtubule dynamics can result from facilitated diffusion of GTP-tubulin to the microtubule ends. Facilitated diffusion can promote microtubule assembly, because, upon encountering a growing nucleus or the microtubule wall, ran...

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Bibliographic Details
Main Authors: Alain Mechulam, Konstantin G Chernov, Elodie Mucher, Loic Hamon, Patrick A Curmi, David Pastré
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2599886?pdf=render

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http://europepmc.org/articles/PMC2599886?pdf=render

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