NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice.

NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice.

Thyrotropin-releasing hormone (TRH) is a major stimulator of thyrotropin-stimulating hormone (TSH) synthesis in the anterior pituitary, though precisely how TRH stimulates the TSHβ gene remains unclear. Analysis of TRH-deficient mice differing in thyroid hormone status demonstrated that TRH was crit...

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Bibliographic Details
Main Authors: Yasuyo Nakajima, Masanobu Yamada, Ryo Taguchi, Nobuyuki Shibusawa, Atsushi Ozawa, Takuya Tomaru, Koshi Hashimoto, Tsugumichi Saito, Takafumi Tsuchiya, Shuichi Okada, Tetsurou Satoh, Masatomo Mori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3392219?pdf=render

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http://europepmc.org/articles/PMC3392219?pdf=render

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