Involvement of phospholipase C in the norepinephrine-induced hypertrophic response in Cardiomyocytes

Involvement of phospholipase C in the norepinephrine-induced hypertrophic response in Cardiomyocytes

Norepinephrine (NE) is known to mediate cardiomyocyte hypertrophy through the G protein coupled a1 -adrenoceptor (a1 -AR) and the activation of the phosphoinositide-specific phospholipase C (PLC). Since the by-products of PLC activity are important downstream signal transducers for cardiac hypertrop...

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Bibliographic Details
Main Authors: Tappia Paramjit S., Elimban Vijayan, Dhalla Naranjan S.
Format: Article
Language:English
Published: Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine 2022-01-01
Series:Scripta Medica
Subjects:
phospholipase c isozymes
norepinephrine
a1-adrenoceptor
cardiomyocytes
experimental models of cardiac hypertrophy
signal transduction
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2022/2490-33292202149T.pdf

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https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2022/2490-33292202149T.pdf

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