Characterization of the microtranscriptome of macrophages infected with virulent, attenuated and saprophyte strains of Leptospira spp.

Leptospirosis is a bacterial zoonosis, caused by Leptospira spp., that leads to significant morbidity and mortality worldwide. Despite considerable advances, much is yet to be discovered about disease pathogenicity. The influence of epigenetic mechanisms, particularly RNA-mediated post-transcription...

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Main Authors: Leandro Encarnação Garcia, Erivelto Corrêa de Araújo Junior, Larissa Martins Melo, Jaqueline Poleto Bragato, Juliana Regina Peiró, Valéria Marçal Félix de Lima, Márcia Marinho, Daniel Robert Arnold, Flavia Lombardi Lopes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6051669?pdf=render