A PK/PD model for the evaluation of clinical rifaximin dosage for the treatment of dairy cow mastitis induced by Escherichia coli

A PK/PD model for the evaluation of clinical rifaximin dosage for the treatment of dairy cow mastitis induced by Escherichia coli

Abstract Escherichia coli (E. coli) is an opportunistic pathogen that can cause clinical mastitis in dairy cows worldwide. Mastitis produces severe symptoms in dairy cows, such as udder inflammation, the production of harmful substances, reduced milk production, and altered milk quality. Intramammar...

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Bibliographic Details
Main Authors: Honglei Wang, Chen Chen, Chunshuang Liu, Xiaojie Chen, Jingju Zhang, Yufeng Wang, Mingyue Han, Yiming Liu, Xiubo Li
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Veterinary Research
Subjects:
Escherichia coli
Mastitis
Rifaximin
PK/PD model
Monte Carlo simulation
Online Access:https://doi.org/10.1186/s12917-022-03564-2

Internet

https://doi.org/10.1186/s12917-022-03564-2

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