Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice.

Ulcerative colitis (UC) is a major form of chronic inflammation that can frequently progress to colon cancer. Several studies have demonstrated massive infiltration of neutrophils and macrophages into the lamina propria and submucosa in the progression of UC-associated colon carcinogenesis. Macropha...

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Bibliographic Details
Main Authors: Kun Shang, Yu-Pan Bai, Chen Wang, Zhen Wang, Hong-Yu Gu, Xiang Du, Xiao-Yan Zhou, Chun-Lei Zheng, Ya-Yun Chi, Naofumi Mukaida, Ying-Yi Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3525572?pdf=render