Genome-wide base editor screen identifies regulators of protein abundance in yeast

Proteins are key molecular players in a cell, and their abundance is extensively regulated not just at the level of gene expression but also post-transcriptionally. Here, we describe a genetic screen in yeast that enables systematic characterization of how protein abundance regulation is encoded in...

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Bibliographic Details
Main Authors: Olga T Schubert, Joshua S Bloom, Meru J Sadhu, Leonid Kruglyak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/79525