Genome-wide base editor screen identifies regulators of protein abundance in yeast
Proteins are key molecular players in a cell, and their abundance is extensively regulated not just at the level of gene expression but also post-transcriptionally. Here, we describe a genetic screen in yeast that enables systematic characterization of how protein abundance regulation is encoded in...
Main Authors: | Olga T Schubert, Joshua S Bloom, Meru J Sadhu, Leonid Kruglyak |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/79525 |
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