The Role of Activating Transcription Factor 3 in Metformin’s Alleviation of Gastrointestinal Injury Induced by Restraint Stress in Mice

The Role of Activating Transcription Factor 3 in Metformin’s Alleviation of Gastrointestinal Injury Induced by Restraint Stress in Mice

Metformin is one of the most commonly used drugs for type 2 diabetes mellitus. In addition to its anti-diabetic property, evidence suggests more potential applications for metformin, such as antiaging, cellular protection, and anti-inflammation. Studies have reported that metformin activates pathway...

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Bibliographic Details
Main Authors: Bijaya Siwakoti, Te-Sheng Lien, You-Yen Lin, Subhashree Pethaperumal, Shih-Che Hung, Der-Shan Sun, Ching-Feng Cheng, Hsin-Hou Chang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
metformin
restraint stress
gastrointestinal injury
gastrointestinal leakage
gastrointestinal epithelial cell
apoptosis
Online Access:https://www.mdpi.com/1422-0067/24/13/10995

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https://www.mdpi.com/1422-0067/24/13/10995

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