SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum.

Positive-strand RNA viruses, a large group including human pathogens such as SARS-coronavirus (SARS-CoV), replicate in the cytoplasm of infected host cells. Their replication complexes are commonly associated with modified host cell membranes. Membrane structures supporting viral RNA synthesis range...

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Bibliographic Details
Main Authors: Kèvin Knoops, Marjolein Kikkert, Sjoerd H E van den Worm, Jessika C Zevenhoven-Dobbe, Yvonne van der Meer, Abraham J Koster, A Mieke Mommaas, Eric J Snijder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18798692/pdf/?tool=EBI