DNA Copy Number Analysis in Gastrointestinal Stromal Tumors Using Gene Expression Microarrays

We report a method, Expression-Microarray Copy Number Analysis (ECNA) for the detection of copy number changes using Affymetrix Human Genome U133 Plus 2.0 arrays, starting with as little as 5 ng input genomic DNA. An analytical approach was developed using DNA isolated from cell lines containing var...

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Bibliographic Details
Main Authors: Cristina R. Antonescu M.D, Kai Wu, Guoliang Leon Xing, Manqiu Cao, Yaron Turpaz, Margaret A. Leversha, Earl Hubbell, Robert G. Maki, C. Garrett Miyada, Raji Pillai
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S387