The Ameliorative Effects of L-2-Oxothiazolidine-4-Carboxylate on Acetaminophen-Induced Hepatotoxicity in Mice

The Ameliorative Effects of L-2-Oxothiazolidine-4-Carboxylate on Acetaminophen-Induced Hepatotoxicity in Mice

The aim of the study was to investigate the ameliorative effects and the mechanism of action of L-2-oxothiazolidine-4-carboxylate (OTC) on acetaminophen (APAP)-induced hepatotoxicity in mice. Mice were randomly divided into six groups: normal control group, APAP only treated group, APAP + 25 mg/kg O...

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Detalles Bibliográficos
Main Authors: Jun Ho Shin, Seon-Il Jang, Sung Zoo Kim, Kwang-Hyun Park, Jiwon Choi
Formato: Artigo
Idioma:English
Publicado: MDPI AG 2013-03-01
Series:Molecules
Subjects:
L-2-oxothiazolidine-4-carboxylate
acetaminophen-induced hepatotoxicity
apoptosis
oxidative stress
antioxidant
Acceso en liña:http://www.mdpi.com/1420-3049/18/3/3467

Internet

http://www.mdpi.com/1420-3049/18/3/3467

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