lptG contributes to changes in membrane permeability and the emergence of multidrug hypersusceptibility in a cystic fibrosis isolate of Pseudomonas aeruginosa

Abstract Purpose In the lungs of cystic fibrosis patients, Pseudomonas aeruginosa is exposed to a myriad of antibiotics leading to alterations in antibiotic susceptibility. This study identifies mutations resulting in hypersusceptibility in isogenic mutants of a P. aeruginosa clinical isolate, PA34....

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Bibliographic Details
Main Authors: Lucas B. Harrison, Randal C. Fowler, Baha Abdalhamid, Anna Selmecki, Nancy D. Hanson
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:MicrobiologyOpen
Subjects:
Online Access:https://doi.org/10.1002/mbo3.844