Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway

Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway

Abstract Background Current studies show that exosomal miRNAs become an important factor in cancer metastasis. Among the many miRNA studies, miR-7-5p has not been thoroughly investigated in breast cancer metastasis. Methods Bioinformatic screening was performed using extant data from the GEO databas...

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Bibliographic Details
Main Authors: Zhaoyi Liang, Lu Liu, Ruixia Gao, Chengchuan Che, Ge Yang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cellular & Molecular Biology Letters
Subjects:
Breast cancer
Exosome
miR-7-5p
RYK
EMT
Atypical WNT pathway
Online Access:https://doi.org/10.1186/s11658-022-00393-x

Internet

https://doi.org/10.1186/s11658-022-00393-x

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