Ferroptosis increases obesity: Crosstalk between adipocytes and the neuroimmune system

Ferroptosis requires not only the accumulation of iron ions, but also changes in many ferroptosis-related regulators, including a decrease in GPX4 and inhibition of SLC7A11 for classical ferroptosis, a deletion of FSP1 or GCH1. Surprisingly, adipose tissue (AT) in the obesity conditions is also acco...

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Bibliographic Details
Main Authors: Sen Zhang, Zhiyuan Sun, Xing Jiang, Zhimin Lu, Ling Ding, Chengzhi Li, Xuewen Tian, Qinglu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049936/full