Ferroptosis increases obesity: Crosstalk between adipocytes and the neuroimmune system
Ferroptosis requires not only the accumulation of iron ions, but also changes in many ferroptosis-related regulators, including a decrease in GPX4 and inhibition of SLC7A11 for classical ferroptosis, a deletion of FSP1 or GCH1. Surprisingly, adipose tissue (AT) in the obesity conditions is also acco...
Main Authors: | Sen Zhang, Zhiyuan Sun, Xing Jiang, Zhimin Lu, Ling Ding, Chengzhi Li, Xuewen Tian, Qinglu Wang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-11-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049936/full |
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