Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome
Introduction Interstitial cystitis/bladder pain syndrome (IC/BPS) manifests as urinary symptoms including urgency, frequency, and pain. The IP4IC Study aimed to establish a urine-based biomarker score for diagnosing IC/BPS. To accomplish this objective, we investigated the parallels and variances be...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-11-01
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| Series: | Digital Health |
| Online Access: | https://doi.org/10.1177/20552076231216280 |
| _version_ | 1797524820708032512 |
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| author | Joseph J. Janicki Elijah P. Ward Sarah N. Bartolone Laura E. Lamb Nitya Abraham Melissa Laudano Christopher P. Smith Kenneth M. Peters Bernadette M.M. Zwaans Michael B. Chancellor |
| author_facet | Joseph J. Janicki Elijah P. Ward Sarah N. Bartolone Laura E. Lamb Nitya Abraham Melissa Laudano Christopher P. Smith Kenneth M. Peters Bernadette M.M. Zwaans Michael B. Chancellor |
| author_sort | Joseph J. Janicki |
| collection | DOAJ |
| description | Introduction Interstitial cystitis/bladder pain syndrome (IC/BPS) manifests as urinary symptoms including urgency, frequency, and pain. The IP4IC Study aimed to establish a urine-based biomarker score for diagnosing IC/BPS. To accomplish this objective, we investigated the parallels and variances between patients enrolled via physician/hospital clinics and those recruited through online crowdsourcing. Methods Through a nationwide crowdsource effort, we collected surveys from patients with history of IC/BPS. Study participants were asked to complete the validated instruments of Interstitial Cystitis Symptom Index (ICSI) and Interstitial Cystitis Problem Index (ICPI), as well as provide demographic information. We then compared the survey responses of patients recruited through crowdsourcing with those recruited from three specialized tertiary care urology clinics engaged in clinical research. Results Survey responses of 1300 participants were collected from all 50 states of the USA via crowdsourcing and 319 from a clinical setting. ICSI and ICPI were similar for IC/BPS patients diagnosed by the physicians in clinic and self-reported by subjects via crowdsourcing stating they have a history of previous physician diagnosis of IC/BPS. Surprisingly, ICSI and ICPI were significantly lower in crowdsourced control than in-clinic control subjects. Conclusion The IP4IC Study provides valuable insights into the similarities and differences between patients recruited through clinics and those recruited through online crowdsourcing. There were no significant differences in disease symptoms among these groups. Individuals who express an interest in digital health research and self-identify as having been previously diagnosed by physicians with IC/BPS can be regarded as reliable candidates for crowdsourcing research. |
| first_indexed | 2024-03-10T09:03:00Z |
| format | Article |
| id | doaj.art-116b8045b1f343df9ab8bb75a1757254 |
| institution | Directory Open Access Journal |
| issn | 2055-2076 |
| language | English |
| last_indexed | 2024-03-10T09:03:00Z |
| publishDate | 2023-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Digital Health |
| spelling | doaj.art-116b8045b1f343df9ab8bb75a17572542023-11-22T06:34:25ZengSAGE PublishingDigital Health2055-20762023-11-01910.1177/20552076231216280Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndromeJoseph J. Janicki0Elijah P. Ward1Sarah N. Bartolone2Laura E. Lamb3Nitya Abraham4Melissa Laudano5Christopher P. Smith6Kenneth M. Peters7Bernadette M.M. Zwaans8Michael B. Chancellor9 Department of Urology, Underactive Bladder Foundation, Pittsburgh, PA, USA Department of Urology, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Department of Urology, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Department of Urology, , Rochester, MI, USA Department of Urology, , The Bronx, NY, USA Department of Urology, , The Bronx, NY, USA Department of Urology, , Houston, TX, USA Department of Urology, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Department of Urology, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA Department of Urology, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USAIntroduction Interstitial cystitis/bladder pain syndrome (IC/BPS) manifests as urinary symptoms including urgency, frequency, and pain. The IP4IC Study aimed to establish a urine-based biomarker score for diagnosing IC/BPS. To accomplish this objective, we investigated the parallels and variances between patients enrolled via physician/hospital clinics and those recruited through online crowdsourcing. Methods Through a nationwide crowdsource effort, we collected surveys from patients with history of IC/BPS. Study participants were asked to complete the validated instruments of Interstitial Cystitis Symptom Index (ICSI) and Interstitial Cystitis Problem Index (ICPI), as well as provide demographic information. We then compared the survey responses of patients recruited through crowdsourcing with those recruited from three specialized tertiary care urology clinics engaged in clinical research. Results Survey responses of 1300 participants were collected from all 50 states of the USA via crowdsourcing and 319 from a clinical setting. ICSI and ICPI were similar for IC/BPS patients diagnosed by the physicians in clinic and self-reported by subjects via crowdsourcing stating they have a history of previous physician diagnosis of IC/BPS. Surprisingly, ICSI and ICPI were significantly lower in crowdsourced control than in-clinic control subjects. Conclusion The IP4IC Study provides valuable insights into the similarities and differences between patients recruited through clinics and those recruited through online crowdsourcing. There were no significant differences in disease symptoms among these groups. Individuals who express an interest in digital health research and self-identify as having been previously diagnosed by physicians with IC/BPS can be regarded as reliable candidates for crowdsourcing research.https://doi.org/10.1177/20552076231216280 |
| spellingShingle | Joseph J. Janicki Elijah P. Ward Sarah N. Bartolone Laura E. Lamb Nitya Abraham Melissa Laudano Christopher P. Smith Kenneth M. Peters Bernadette M.M. Zwaans Michael B. Chancellor Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome Digital Health |
| title | Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome |
| title_full | Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome |
| title_fullStr | Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome |
| title_full_unstemmed | Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome |
| title_short | Comparing online crowdsourcing with clinic patient enrollment: Findings from the IP4IC Study on interstitial cystitis/bladder pain syndrome |
| title_sort | comparing online crowdsourcing with clinic patient enrollment findings from the ip4ic study on interstitial cystitis bladder pain syndrome |
| url | https://doi.org/10.1177/20552076231216280 |
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