<i>MhcII</i> Regulates Transmission of α-Synuclein-Seeded Pathology in Mice

<i>MhcII</i> Regulates Transmission of α-Synuclein-Seeded Pathology in Mice

MHCII molecules, expressed by professional antigen-presenting cells (APCs) such as T cells and B cells, are hypothesized to play a key role in the response of cellular immunity to α-synuclein (α-syn). However, the role of cellular immunity in the neuroanatomic transmission of α-syn pre-formed fibril...

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Bibliographic Details
Main Authors: Elsa Gonzalez De La Cruz, Quan Vo, Katie Moon, Karen N. McFarland, Mary Weinrich, Tristan Williams, Benoit I. Giasson, Paramita Chakrabarty
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
synuclein
Lewy body
transmission
prion
MhcI
inflammation
Online Access:https://www.mdpi.com/1422-0067/23/15/8175

Internet

https://www.mdpi.com/1422-0067/23/15/8175

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