Central nervous system-related safety and tolerability of add-on ketamine to standard of care treatment in treatment-resistant psychotic depression in patients with major depressive disorder and bipolar disorder

BackgroundPsychotic treatment-resistant depression represents a complex and challenging form of mood disorder in clinical practice. Despite its severity, psychotic depression is frequently underdiagnosed and inadequately treated. Ketamine has demonstrated rapid and potent antidepressant effects in c...

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Bibliographic Details
Main Authors: Maria Gałuszko-Wȩgielnik, Katarzyna Jakuszkowiak-Wojten, Mariusz Stanisław Wiglusz, Wiesław Jerzy Cubała, Michał Pastuszak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1214972/full