Longitudinal Studies on Alzheimer Disease Mouse Models with Multiple Tracer PET/CT: Application of Reduction and Refinement Principles in Daily Practice to Safeguard Animal Welfare during Progressive Aging

Longitudinal Studies on Alzheimer Disease Mouse Models with Multiple Tracer PET/CT: Application of Reduction and Refinement Principles in Daily Practice to Safeguard Animal Welfare during Progressive Aging

Longitudinal studies on mouse models related to Alzheimer disease (AD) pathology play an important role in the investigation of therapeutic targets to help pharmaceutical research in the development of new drugs and in the attempt of an early diagnosis that can contribute to improving people’s quali...

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Bibliographic Details
Main Authors: Giovanna Palumbo, Lea Helena Kunze, Rosel Oos, Karin Wind-Mark, Simon Lindner, Barbara von Ungern-Sternberg, Peter Bartenstein, Sibylle Ziegler, Matthias Brendel
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Animals
Subjects:
refinement
enrichment environment
reduction
small animal positron emission tomography
longitudinal study
Alzheimer disease
Online Access:https://www.mdpi.com/2076-2615/13/11/1812

Internet

https://www.mdpi.com/2076-2615/13/11/1812

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